Every tradition of Wicca works specifically with their own patron god and goddess. In some traditions there are more than one pairing; mine works regularly with 8 deities, although one god and one goddess is given prominence at a time. Outside of Traditional Craft, pagans/wiccans may work with any deity that is willing to work with them.
It is not recommended to “mix pantheons” so as to avoid cultural conflict amongst gods that may be invited into circle. I would also caution be assured of a harmonious relationship between deities of similar cultural source; inviting Athena and Poseidon to the same party may be ill advised. Thor and Freya would probably work ok together, although Freya’s traditional consort is Frey, so that might work a bit better.
Not all Witches work with Deity, but almost all Wicca do.